DIGGER
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Network-Level Analysis
Query interactions of multiple isoforms and generate a specific subnetwork from a list of protein variants or transcripts.
Option 1
: Enter a list of Ensembl IDs (genes, transcripts or proteins)
[Example 1: Specific interaction between two Isoforms]
[Example 2: Interaction between multiple isoforms]
[Example 3: Transcriptomics data (differentially expressed transcripts in normal/tumor samples 'BRCA cancer')]
ENSP00000009105 ENSP00000009180 ENSP00000009530 ENSP00000009589 ENSP00000010132 ENSP00000010299 ENSP00000010404 ENSP00000011292 ENSP00000011473 ENSP00000011619 ENSP00000011653 ENSP00000011684 ENSP00000011691 ENSP00000011700 ENSP00000011898 ENSP00000011989 ENSP00000012049 ENSP00000012134 ENSP00000012443 ENSP00000013034 ENSP00000013070 ENSP00000013125 ENSP00000013222 ENSP00000013807 ENSP00000014914 ENSP00000014930 ENSP00000014935 ENSP00000016171 ENSP00000016913 ENSP00000016946 ENSP00000017003 ENSP00000019019 ENSP00000019103 ENSP00000019317 ENSP00000020673 ENSP00000020926 ENSP00000020945 ENSP00000022615 ENSP00000023064 ENSP00000023897 ENSP00000023939 ENSP00000024061 ENSP00000025008 ENSP00000025301 ENSP00000025399 ENSP00000026218 ENSP00000029410 ENSP00000468864 ENSP00000033079 ENSP00000034275 ENSP00000035307 ENSP00000037243 ENSP00000037502 ENSP00000037869 ENSP00000038176 ENSP00000039007 ENSP00000039989 ENSP00000040584 ENSP00000040663 ENSP00000040738 ENSP00000040877 ENSP00000042381 ENSP00000043402 ENSP00000044462 ENSP00000045347 ENSP00000046087 ENSP00000046640 ENSP00000046794 ENSP00000052569 ENSP00000052754 ENSP00000053243 ENSP00000053468 ENSP00000053469 ENSP00000053867 ENSP00000054650 ENSP00000054666 ENSP00000054668 ENSP00000054950 ENSP00000055077 ENSP00000055335 ENSP00000055682 ENSP00000056217 ENSP00000056233 ENSP00000057513 ENSP00000060969 ENSP00000061240 ENSP00000064571 ENSP00000064778 ENSP00000064780 ENSP00000066544 ENSP00000070846 ENSP00000072516 ENSP00000072644 ENSP00000072869 ENSP00000074304 ENSP00000075120 ENSP00000075322 ENSP00000075430 ENSP00000075503 ENSP00000078429 ENSP00000078445 ENSP00000078527 ENSP00000080059 ENSP00000081029 ENSP00000083182 ENSP00000084795 ENSP00000084798 ENSP00000085068 ENSP00000085079 ENSP00000085219 ENSP00000155093 ENSP00000155674 ENSP00000155840 ENSP00000155926 ENSP00000156084 ENSP00000156109 ENSP00000156471 ENSP00000156626 ENSP00000156825 ENSP00000157600 ENSP00000157812 ENSP00000158166 ENSP00000158526 ENSP00000158762 ENSP00000158771 ENSP00000159087 ENSP00000159111 ENSP00000160262 ENSP00000160298 ENSP00000160373 ENSP00000160382 ENSP00000160713 ENSP00000160740 ENSP00000160827 ENSP00000161006 ENSP00000161559 ENSP00000161863 ENSP00000162044 ENSP00000162330 ENSP00000162391 ENSP00000162749 ENSP00000163416 ENSP00000164024 ENSP00000164133 ENSP00000164139 ENSP00000164227 ENSP00000164247 ENSP00000164305 ENSP00000164640 ENSP00000165698 ENSP00000166139 ENSP00000166244 ENSP00000166345 ENSP00000166534 ENSP00000167106 ENSP00000167462 ENSP00000167586 ENSP00000167588 ENSP00000168216 ENSP00000168712 ENSP00000168977 ENSP00000169293 ENSP00000169298 ENSP00000169551 ENSP00000170150 ENSP00000170168 ENSP00000170447 ENSP00000170564 ENSP00000170630 ENSP00000171111 ENSP00000171887 ENSP00000172229 ENSP00000172853 ENSP00000173229 ENSP00000173527 ENSP00000173898 ENSP00000174618 ENSP00000174653 ENSP00000175091 ENSP00000175506 ENSP00000175756 ENSP00000176183 ENSP00000176195 ENSP00000176643 ENSP00000176763 ENSP00000177648 ENSP00000177694 ENSP00000177742 ENSP00000178638 ENSP00000178640 ENSP00000179259 ENSP00000180166 ENSP00000180173 ENSP00000181383 ENSP00000181796 ENSP00000181839 ENSP00000182377 ENSP00000182527 ENSP00000183605 ENSP00000184183 ENSP00000184266 ENSP00000184956 ENSP00000185150 ENSP00000185206 ENSP00000186436 ENSP00000187397 ENSP00000187608 ENSP00000187762 ENSP00000187910 ENSP00000188312 ENSP00000188376 ENSP00000188403 ENSP00000188790 ENSP00000189444 ENSP00000189978 ENSP00000190165 ENSP00000190611 ENSP00000190983 ENSP00000191018
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This option supports the visualization of up to 2000 genes/transcripts.
Make sure all the inputs correspond to Ensembl IDs and do not mix genes with transcript IDs.
Option 2
: Upload a file with transcript counts
Upload a transcript count file
Select transcript count file
Specify the maximum number of transcripts
This option supports the output of tools such as Cufflinks and Kallisto (examples:
1
or
2
)
The "maximum number of transcripts" refers to the number of transcripts DIGGER will select when building the sub-network, based on the highest scoring transcripts.
The uploaded file can be either a comma or tab separated table containing Ensembl transcript IDs and counts. The first column of your file must correspond to Ensembl transcript IDs (can have any column name) and there must be a column named either 'tpm', 'counts' or 'FPKM'.
Submit